Blog
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
Blog
Powered by PacBio: Selected publications from June 2024
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
Going beyond the “needle in a haystack” with Onso short-read sequencing
Onso short-read sequencing systems are no longer available through PacBio We’re thrilled to have recently launched our summer promotions for Onso sequencing. These offers open the door for…
Winning human RNA SMRT Grant proposals announced
If you had the chance, how would you elevate your human genomics research using highly-accurate full-length isoform-level sequencing? We posed that question to researchers in January with the…
Sequencing 101: Metagenome-assembled genomes
Microorganisms form the foundations of life on Earth. They shaped our planet long before we were here, and continue to shape our environments and our lives. Understanding microbial…
Powered by PacBio: Selected publications from May 2024
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
Customer success story: Maryland Genomics shines by tackling tough samples with HiFi sequencing
Getting DNA and high-quality sequence data out of challenging samples is Maryland Genomics’ superpower. As part of the Institute for Genome Sciences (IGS) at the University of Maryland School of…
Long-read sequencing myths: debunked. Part 6 — cell & gene therapy
Cell and gene therapy research is crucial for biopharma development, with HiFi long-read sequencing significantly enhancing many sequencing applications throughout the process. Even though AAV sequencing is one of…
Long-read sequencing myths: debunked. Part 5 — microbiology
The organisms you study might be tiny, but the importance of the work you do is anything but. PacBio HiFi sequencing brings the microscopic world into sharp focus, offering…
New hope for neurodegenerative diseases
PacBio PureTarget amplification-free targeted sequencing makes cutting edge advancements in dementia research a possibility. Four years ago neurologist Claire Clelland, MD, PhD, and her Laboratory at the University of…
Powered by PacBio: Selected publications from April 2024
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
Long-read sequencing myths: debunked.
Part 4 — plant and animal
The world is moving at a fast pace, isn’t it? Climate shifts, growing populations, and changing ecosystems are stacking up some serious challenges for species all over the planet, including…
Kinnex in three acts: full-length RNA sequencing for human disease research
Alternative splicing occurs when exons from the same gene combine in different ways, resulting in different (but related) RNA transcript isoforms, which in turn create different proteins with distinct structures…
Long-read sequencing myths: debunked.
Part 3 — cancer genomics
The complexities of cancer biology are famously tricky to decipher. Peering into the murky cancer genome and making sense of tumor mechanisms has long been the goal of researchers…
Long-read sequencing myths: debunked.
Part 2 — human genomics
Hearing “the end of the beginning” or “the dawn of a new era” might sound like a grandiose way to describe a scientific milestone. Would it surprise you to…
Powered by PacBio: Selected publications from March 2024
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…