American Association for Cancer Research® (AACR) Annual Meeting 2026
San Diego, CA
April 17-22, 2026
Booth #3754
American Association for Cancer Research® (AACR) Annual Meeting 2026
San Diego, CA
April 17-22, 2026
Booth #3754
Join us
Discover how cancer researchers are advancing oncology research with PacBio HiFi sequencing. Delivering industry-leading long-read accuracy and comprehensive variant detection, HiFi sequencing reveals the full spectrum of cancer biology including complex structural variants, repeat expansions, gene fusions, and epigenetic modifications in a single, unified workflow. Ongoing innovations in chemistry, throughput, and analysis are making tumor profiling more scalable and cost-effective than ever. Whether you are characterizing complex cancer genomes, uncovering novel fusion events, resolving challenging genomic regions, or exploring methylation patterns alongside structural variation, HiFi sequencing provides a complete and confident view of cancer biology.
Visit us at booth #3754 to meet PacBio experts, see live demonstrations of our Vega sequencing system, and learn how HiFi sequencing can empower your genetic testing workflows.
Stay connected for the latest updates, sessions, and opportunities to connect with PacBio at AACR 2026.
We are excited to learn about your sequencing projects and research.
PacBio Booth #3754 hours:
April 19: 12:00 PM – 5:00 PM
April 20: 9:00 AM – 5:00 PM
April 21: 9:00 AM – 5:00 PM
April 22: 9:00 AM – 12:00 PM
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WORKSHOP PRESENTATION
Seeing cancer more completely: a HiFi approach to cancer genomics
LOCATION: Theater E on Tuesday April 21st, 2026 from 12:30-1:30PM
Disentangling the molecular drivers of cancer requires a complete and accurate understanding of somatic genomic alterations that extend beyond single nucleotide variants and small indels. Structural variants, copy number changes, repetitive elements, DNA methylation, and haplotype context are central to cancer biology and clinical decision-making, yet are frequently missed or fragmented across multiple assays such as short-read sequencing, cytogenetics, and FISH.
Highly accurate long-read sequencing with PacBio HiFi enables consolidation of these disparate workflows into a single assay, providing a comprehensive view of the cancer genome and epigenome. By combining long read lengths with exceptional accuracy, HiFi sequencing resolves complex structural variation, enables phasing, and captures epigenetic information in the same experiment offering insights that are difficult to achieve in one test with legacy methods.
Join PacBio to learn how HiFi sequencing is enabling a better way to study and translate cancer genomics, from research applications such as structural variations in leukemia to pre-clinical workflows aiming to replace legacy testing. This workshop will highlight how assay consolidation with HiFi sequencing is advancing our ability to understand cancer biology while simplifying translational lab workflows.
Speakers:
POSTER PRESENTATIONS
Seeing cancer more completely: a HiFi approach to cancer genomics
A new workflow for FFPE tumor samples enables a streamlined solution for structural variant detection and phasing of somatic mutations through long-read sequencing
Session Category: Molecular / Cellular Biology and Genetics
Title: Genomic Profiling to Understand Cancer Biology
Time: 4/20/2026 2:00pm-5:00pm
Location: Poster Section 22
Poster Board Number: 18
Poster Number: 3253
Presenter: Camille Conner
Hunting for microsatellite instability in long-read data with Owl
Session Category: Bioinformatics / Computational Biology / Systems Biology / Convergent Science
Title: New Software Tools for Data Analysis
Time: 4/21/2026 2:00pm-5:00pm
Location: Poster Section 4
Poster Board Number: 15
Poster Number: 5510
Presenter: Zev Kronenberg
PARTNER POSTER PRESENTATIONS
Resolving genome regulatory complexity with new multiomic
long-read sequencing tools for chromatin state and genetic variation
Session Category: Molecular / Cellular Biology and Genetics
Time: 4/20/2026 2:00pm-5:00pm
Location: Poster Section 21
Poster Board Number: 7
Poster Number: 3225
Presenter: Lu Sun, Epicypher
Cancer gene variant identification and functional interpretation using long-read RNA sequencing with FLAIR3
Session Category: Sequence Analysis
Time: 4/20/2026 9:00am-12:00pm
Location: Poster Section 6
Poster Board Number: 8
Poster Number: 1501
Presenter: Angela Brooks, PhD, UCSC
Long-read sequencing of 15 Ewing sarcoma cell lines uncovers extensive GGAA microsatellite variation shaping the landscape of EWSR1::FLI1 binding
Session Category: Bioinformatics / Computational Biology / Artificial Intelligence / Data Science
Time: 4/20/2026 9:00am-12:00pm
Location: Poster Section 6
Poster Board Number: 3
Poster Number: 1496
Presenter: Mitchell Machiela, PhD, National Cancer Institute
CASTLE: long-read sequencing panel of cancer cell lines to improve standards of somatic variant calling and benchmarking
Session Category: Bioinformatics / Computational Biology / Artificial Intelligence / Data Science
Time: 4/20/2026 9:00am-12:00pm
Location: Poster Section 6
Poster Board Number: 17
Poster Number: 1510
Presenter: Mikhail Kolmogorov, PhD, NIH-NCI
Comprehensive profiling of circulating tumor DNA in blood enables sensitive detection and genomic characterization of HPV cancer and precancer
Session Category: Category: Circulating Nucleic Acids 1
Time: 4/20/2026 9:00am-12:00pm
Location: Poster Section 42
Poster Board Number: 18
Presenter: Qin Wang, Massachusetts Eye and Ear
Utility of long-read RNA-sequencing for isoform and fusion discovery in lung cancer
Session Category: Category: Genetic and Transcriptomic Dissection of Cancer Evolution
Time: 4/21/2026 200pm-5:00pm
Location: Poster Section 21
Poster Board Number: 3
Poster Number: 5915
Presenter: Alice Berger, PhD, Fred Hutchinson Cancer Center
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