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SEQUENCING PLATFORM COMPARISON

Why labs are switching to HiFi sequencing

More accurate than Nanopore. More complete than
SBS-based proximity mapped read technology. Less expensive than both. Compare the platforms and then download the app brief.

$345

genome on PacBio HiFi (SPRQ-Nx)

$395

genome on Illumina TruPath

~$1,000

genome on Oxford Nanopore

The economics of HiFi sequencing  just changed: Long-read genomes at $345.

The latest SPRQ-Nx multi-use SMRT Cells for the Revio system deliver gold-standard HiFi reads using only 500 ng DNA. HiFi reads give genomic users a clear path to more reliable detection of all variant types, built-in methylation insights, and scalable, cost-efficient workflows for everything from discovery to routine use.

Access your app brief

Cost data, variant benchmarks, and beta site results all in one document.

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HEAD-TO-HEAD

Platform comparison at a glance

The metrics that matter for sequencing platform selection – cost, accuracy, methylation, phasing, and application breadth.

“It was shockingly easy, honestly. We expected more issues than we had.
So it was a great experience for us.”

  • Margaret Gibson
    Children’s Mercy Hospital – on adopting SPRQ-Nx

Get the full comparison in one document

The SPRQ-Nx chemistry application brief includes cost data, variant benchmarks, and beta site results you can share with your team.

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