Long-read sequencing myths: debunked. Part 5 — microbiology
The organisms you study might be tiny, but the importance of the work you do is anything but. PacBio HiFi sequencing brings the microscopic world into sharp focus, offering…
This blog features voices from PacBio — and our partners and colleagues — discussing the latest research, publications, and updates about HiFi sequencing.
The organisms you study might be tiny, but the importance of the work you do is anything but. PacBio HiFi sequencing brings the microscopic world into sharp focus, offering…
PacBio PureTarget amplification-free targeted sequencing makes cutting edge advancements in dementia research a possibility. Four years ago neurologist Claire Clelland, MD, PhD, and her Laboratory at the University of…
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
The world is moving at a fast pace, isn’t it? Climate shifts, growing populations, and changing ecosystems are stacking up some serious challenges for species all over the planet, including…
Alternative splicing occurs when exons from the same gene combine in different ways, resulting in different (but related) RNA transcript isoforms, which in turn create different proteins with distinct structures…
The complexities of cancer biology are famously tricky to decipher. Peering into the murky cancer genome and making sense of tumor mechanisms has long been the goal of researchers…
Hearing “the end of the beginning” or “the dawn of a new era” might sound like a grandiose way to describe a scientific milestone. Would it surprise you to…
PacBio HiFi sequencing technology continues to be the tool of choice for genomics professionals working at the forefront of discovery, enabling them to pursue new avenues of exploration across diverse…
In the fast-evolving landscape of genomics, the pace can be dizzying, and the fear of falling behind is real. Genomic research undergoes constant change, so if you want to…
For years, exome sequencing has been a popular method for identifying disease-causing variants, both in clinical and research settings, due to its relative affordability and practicality when compared to whole-genome…
Cristian Tomasetti, PhD, discusses the positive impact of super-accurate PacBio short reads on the development of cancer early detection assays at TGen and City of Hope.
Get a quick summary of the hottest scientific articles and preprints to incorporate PacBio HiFi sequencing for the month of February 2024.
In honor of Rare Disease Day 2024, we spoke with Dr. Kym Boycott of the Care4Rare Consortium about how HiFi sequencing has helped deliver answers to families impacted by rare genetic diseases.
When new sequencing instruments are released, great leaps in genomics capabilities follow. But did you know that for some applications like 16S microbiome research, gene annotation, or cancer transcriptomics, “new-instrument-level” performance can be achieved with something as simple as an off-the-shelf kit?
According to the United States’ National Institutes of Health (NIH), an estimated 7,000 rare diseases collectively impact between 3.5% to 5.9% of the global population, equating to 263 to 446…
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