The value of Q40+ sequencing accuracy with SBB for liquid biopsy

Liquid biopsy is revolutionizing cancer research through non-invasive detection of tumor DNA in the blood. However, sequencing errors introduced by traditional next-generation sequencing can mimic real mutations, obscuring the true signal. The PacBio Onso short-read sequencing system, powered by our highly accurate SBB technology, can reduce false positives and improve sensitivity for detecting rare variants in ctDNA, potentially enabling a new generation of liquid biopsy assays for more sensitive tumor DNA detection.