Sequencing by binding (SBB®) delivers unprecedented NGS accuracy

Jonas Korlach, Chief Scientific Officer at PacBio reports at AGBT 2022 on how the company’s new short-read platform, built around sequencing by binding (SBB), promises significant accuracy improvements over conventional NGS approaches. Beyond unparalleled accuracy, he further describes key design principles including mid- to high-throughput NGS platform, optical and mechanical innovations, and scalability, flexibility, and cost-optimization. Korlach also shares specific examples illustrating the unprecedented performance of the platform.