Wednesday, March 29, 2017

IGV 3 Improves Support for PacBio Long Reads

The recent beta release of version 3 of the popular genome browser IGV greatly improves support for PacBio data [1].  The long reads (up to 50 kb) and random error profile of PacBio SMRT® sequencing facilitate new applications in genome assembly, structural variant discovery, and haplotype phasing.  These unique properties and applications benefit from customized data visualization. IGV 3 extends support for PacBio long reads with: performance improvements to enable viewing variants at multi-kilobase scales; a “quick consensus” mode that suppresses single read random errors; labels for large insertion and deletion structural variants; and “group by base” to explore haplotype…

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