Tuesday, April 11, 2017

Crow Genome Analysis Combines Assemblies to Spot Tandem Arrays

[caption id="attachment_16661" align="alignright" width="300"] Photo by Jonn Leffmann[/caption] A new publication in Genome Research shows how the use of SMRT Sequencing, in combination with other technologies, can reveal far more about repetitive DNA and structural variants than short-read sequencing alone. In this paper, scientists compared genome assemblies produced with short reads, long reads, and optical maps to understand the performance of each approach. From Uppsala University, the University of Munich, and Bionano Genomics, the team studied the Eurasian crow for this project. The resulting paper, “Combination of short-read, long-read and optical mapping assemblies reveals large-scale tandem repeat arrays with population…

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