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2020 Local SMRT Grant Winners
The University of Queensland – School of Chemistry and Molecular Biosciences
Awarded to Professor Glenn King at the Institute for Molecular Bioscience for his project “‘Deadly Genes: Exploring the Genome of the lethal Australian Box Jellyfish”. This project will use HiFi sequencing on the PacBio Sequel II System to provide a foundational resource for the global research community to resolve the function of individual venom components, develop improved antivenoms and/or therapeutic adjuncts. This will also help in better understanding the evolution of jellyfish and, more broadly, related cnidarians such as corals and sea anemones.
The University of Tokyo – Research Center for Advanced Science and Technology
Awarded to Dr. Aya Nonaka at the Genome Science Laboratory for her project “Involvement of isoform genes in heterogeneous alpha-fetoprotein producing gastric cancer (AFPGC)”, which will include single-cell Iso-Seq analysis of AFPGC organoids using a PacBio Sequel II System to identify the contribution of isoforms to the differentiation of AFPGC.
2019 Local SMRT Grant Winners
NYU Langone Health – Genome Technology Center
Awarded to Dr. Ken Cadwell at the Skirball Institute of Biomolecular Medicine for his project “Whole genome sequencing of helminth-associated Clostridia species” and Dr. Ralf Duerr at the Department of Pathology for his project “Unraveling functional HIV-1 sequence marks that are associated with beneficial disease parameters using SMRT Sequencing.”
University of Wisconsin-Madison – UWBC DNA Sequencing Facility
Awarded to Dr. Linda E. Graham at the Department of Botany for her project “Long-read shotgun metagenomic analysis of a rare plant key to understanding plant microbiome evolution and conservation of biodiversity on tribal land” and Dr. Steven Baker at the Department of Medical Microbiology and Immunology for his project “High-resolution analysis of immune-activated alternative splicing.”
Cold Spring Harbor Laboratory – Next Generation Genomics Core
Awarded to Dr. Quan Long of the University of Calgary in the Department of Biochemistry and Molecular Biology for his project “Analyzing within-host evolution of HIV.”
McMaster University – McMaster Genome Facility
Awarded to Dr. Hindra Hindra of Dr. Marie Elliot’s lab at the Department of Biology and the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University for his project “Unlocking the treasure chest: New antibiotic discovery and characterization using PacBio-enabled genome sequences.”
Virginia Commonwealth University – VCU Genomics Core
Awarded to Dr. Michael McVoy at the Department of Pediatrics, Division of Infectious Diseases for his project “In Vitro Evolution of Human Cytomegalovirus” and Dr. Robin Chan of the Center for Biomarker Research and Precision Medicine for her project “DNA Methylation (m6dA) in the Human Brain.”
2018 Local SMRT Grant Winners
University of Oregon – Genomics & Cell Characterization Core Facility (GC3F)
University of California Irvine – UCI Genomics High-Throughput Facility (GHTF)
Dr. Anand Ganesan and Jessica Flesher for their work studying wildtype and model knockout isoforms of MITF-A and MITF-M in rats.
University of Georgia – Georgia Genomics and Bioinformatics Core (GGBC)
Awarded to Emily Loring Dittmar for her project “Comparative Genomics of the Major Filamentous Pathogens of Sunflower.”