When Accuracy Matters – Scientists Choose HiFi Sequencing
At PacBio we are passionate about accuracy in sequencing data. If your research could benefit from highly accurate long-read sequencing apply for this SMRT Grant!
Why is Accuracy So Important?
Because you need sequencing data you can trust for advanced biological insights.
HiFi reads are both long (up to 25 kb) and highly accurate (>99.9%) to generate complete, contiguous, and correct assemblies of even the most complex genomes with minimal compute resources.
“If your genome isn’t HiFi, it’s no longer reference grade.”
— Kevin McKernan, Medicinal Genomics
HiFi reads offer best-in-class detection of all variant types including single nucleotide variants (SNVs), indels, and structural variants (SV).
“HiFi Reads really allow us to call accurate structural variations and other types of variations that you can’t actually see in something like with short-read sequencing.”
— Jeremy Schmutz, Faculty Investigator, HudsonAlpha Institute of Biotechnology
Learn more about HiFi sequencing
Explore the range of HiFi sequencing applications
Get to know all all the benefits of HiFi sequencing
|Whole Genome Sequencing for generation of reference-quality de novo genome assemblies|
|Variant Detection for comprehensive detection of all variants – from SNVs to structural variants|
|RNA Sequencing to gain a complete view of transcript isoform diversity – no assembly required|
|Targeted Sequencing for accurate discovery and detection of all variant types even in the hardest to reach regions of the genome|
|Complex Populations to resolve the complexity of bacterial, viral, and cancer cell populations|
|Epigenetics through direct detection of DNA modification during sequencing|
The 2021 HiFi for Accuracy SMRT Grant Program is Now Closed
Thank you for your interest in the HiFi for Accuracy SMRT Grant. We are received hundreds of submissions from scientists worldwide who are excited to use HiFi sequencing in their research. We will announce the winners in July!
Learn about upcoming SMRT Grant Programs
Want to learn more about how HiFi sequencing can empower your science?
Connect with a PacBio scientist to discuss your project or instrument needs.
Learn about Our Co-Sponors
|The DNA Sequencing Center at Brigham Young University in Provo, Utah was established to support the research needs of faculty and students including advising and training in DNA and RNA sample preparation and library construction. They provide high-quality DNA sequencing results to fit the budget and specifications for researchers around the world and have many years of experience in sequencing a variety of organisms including bacteria, invertebrates, vertebrates, and plants.|
|The CCGA is one of four German Research Foundation funded next generation sequencing centres with the mission to strengthen the biological and medical infrastructure in Germany. Their sequencing services comprise short and long-read sequencing technologies as well as bioinformatics support.|
|BIOTOOLS specializes in bringing scientists total solution products for all applications of biomedical research from DNA to proteins, including molecular biology reagents (immunology, PCR, qPCR, and nucleic acid purification kits, etc.). They provide customized products such as miRNA mimics and inhibitors, siRNA, peptide and service platform including Next Generation Sequencing, Third Generation Sequencing, Proteomics analysis, Metabolomics analysis, and other services.|