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お問い合わせ

動植物の成長に影響を与える微生物の探索

微生物の相互作用と完全なゲノム情報の理解は、農作物生産の向上、家畜における健康と生産の改善、野生動物における保護に大きく寄与します。

未知の領域にブレイクスルー

PacBioの1分子リアルタイム(SMRT)シークエンスを使えば、動植物の成長、健康、生産にインパクトを与える微生物の包括的な像を捉えることができます。PacBioのシステムでは下記の解析が可能です。

スポットライト:海洋微生物における生物種レベルの解像度

サンゴに関連する微生物集団の複雑なエコシステムを解明し、インド洋における多様性と構造を理解。PacBioで行った完全長16S rRNAシークエンスにより、多様な生息地における微生物の保存されたプロファイルが明らかになりました。

Pootakham, W. et al., 2017. High resolution profiling of coral-associated bacterial communities using full-length 16S rRNA sequence data from PacBio SMRT sequencing system. Scientific Reports, 7(1), p.2774.

スポットライト:系統解析により微生物生物種内の変化を捉える

全ゲノムシークエンスでウシから単離した微生物を比較。株の病原性にインパクトを与える遺伝子数、再構成の変化により、生物種内で大きな多様性を発見しました。

Dickey, A.M. et al., 2016. Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle. Veterinary Research, 47(1), p.31.

SMRTシークエンスで行う動植物と微生物研究について、ぜひお問い合わせください。

Selected Resources