Connect with the PacBio Community

AAV Capsid discovery and design – Novel sequencing approaches

May 01, 2024

Americas/Europe broadcast: Wednesday, May 1, 9 AM PDT | 12 PM EDT | 5 PM BST

HiFi sequencing emerges as a critical technology in this quest, offering exceptional accuracy in sequencing the full-length AAV capsid gene. This capability is crucial for enabling whole-capsid engineering, thereby enhancing the potential safety and efficacy of gene therapy products. Our webinar will explore these innovative sequencing approaches, shedding light on their transformative potential in AAV capsid design. Join us and embrace the future with HiFi sequencing, offering game-changing accuracy and visibility essential for groundbreaking gene therapy research.

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Understanding full-length single-cell RNA-seq of immune cells in cardiovascular diseases

May 02, 2024

Europe broadcast: Thursday, May 2 | 4:00 PM CEST
Americas broadcast: Thursday, May 2 | 9:00 AM PDT

Full-length isoform sequencing enables you to robustly identify new isoforms and study isoform dynamics in single-cell populations. Find out how concatenating isoforms can deliver a 16-fold throughput increase compared to un-concatenated libraries – without losing accuracy or full-length isoform information.

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Comprehensive variant detection in pediatric leukemia research with accurate long-read whole genome sequencing

May 08, 2024 - May 09, 2024

Americas/Europe broadcast: Wednesday, May 8, 8:00 AM PDT | 4:00 PM BST
Asia-Pacific broadcast: Thursday, May 9, 11:00 AM SGT

Accurate long-read sequencing from PacBio (HiFi sequencing) offers whole-genome and transcriptome sequencing for the detection of DNA and RNA variants, including methylation. In this webinar you will hear about how HiFi sequencing enabled the detection of variants in pediatric leukemia samples that were missed by other technologies, bringing us a step closer to the promise of a single comprehensive assay.

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Characterizing C9ORF72 repeat expansions and transcripts using HiFi sequencing

May 22, 2024 - May 23, 2024

Americas/Europe broadcast: Wednesday, May 22, 8:00 AM PDT | 11:00 AM EDT | 4:00 PM BST
Asia-Pacific broadcast: Thursday, May 23, 11:00 AM SGT

HiFi sequencing’s precision and comprehensive coverage make it an invaluable tool in the genetic researcher’s arsenal. The PureTarget repeat expansion panel, with its tailored approach to sequencing regions known for repeat expansions, and the Kinnex kit, dedicated to uncovering the spectrum of transcriptomic diversity, represent the forefront of these efforts. Together, they offer a synergistic solution that enables researchers to explore the genetic and epigenetic intricacies of neurodegenerative diseases with unprecedented clarity.

This webinar aims to dive deep into these technologies, showcasing their potential to revolutionize our understanding and treatment of complex genetic conditions.

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