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用单分子实时(SMRT)测序推动基因组学

为了克服基因组学领域的固有挑战,我们努力开发新技术来拓展测序的边界。SMRT测序正是这种努力的结晶,它利用DNA复制的天然过程,并实时观察DNA的合成。这种独特的技术为具有创新精神的科学家提供装备并带来推动遗传探索所需的结果。

SMRT测序建立在两个关键创新之上:零模波导孔(ZMW)和核苷酸焦磷酸链。ZMW使得光仅照射在固定DNA聚合酶/模板复合物的孔的底部。当DNA聚合酶产生一条完全天然的DNA链时,可观察/检测到被固定在复合物上的核苷酸焦磷酸链。

SMRT测序的优势

SMRT测序是各种测序应用的理想之选,它提供许多好处,包括:

SMRT测序概述

若有意获取更多信息以将SMRT测序融入您的研究工作中,请联系我们

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