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更全面地了解遗传多样性

深入了解生物学性状背后的遗传学,是解决许多农业、工业和环境挑战的关键因素。


单分子实时(SMRT)测序让人们全面了解高度复杂的大型动植物基因组的遗传多样性,是从事进化研究和农业基因组学的研究人员的理想之选。该技术正推动研究探索,并可获得宝贵认识,以支持作物、牲畜和工业产品的改良。

PacBio系统适合广泛的应用,让科学家能够:

02_AgBioSpot01

以高分辨率探索进化和多样性

许多种、属甚至科通常只有单一、片段化的参考基因组,往往限制了深入探索的可能性。过去使用的短读长、有偏倚的下一代测序读取序列往往只能获得草图级别的低质量基因组。高质量的参考基因组及基于证据的基因注释带来了遗传多样性的完整视图,让科学家能够做出新颖而有意义的发现。

02_AgBioSpot02

发现关键基因以改良农产品

无论是农作物或牲畜的培育、疾病的预防和治疗,还是害虫的抵御,在设计高性能的产品时都离不开对遗传组分的深入了解。高通量、长读长且经济高效的测序能够最完整、最准确地分析感兴趣的基因,从而更快响应市场需求。

02_AgBioSpot03

为工业应用精确改造生物体

通过优化现有的生化途径或设计新的途径,科学家将微生物和植物转化成安全独立的制造中心。SMRT测序为测序单个生物体或解析微生物群落提供了一个无缝流程,可实现完整且准确的基因组组装,为改造打下基础。

SMRT测序项目计算器

将您感兴趣的植物或动物基因组告知我们,以估算在Sequel系统上开展下列应用所需的时间和材料:

研究聚焦:填补缺口,推进科学

一篇在《科学》上新发表的论文突出强调了PacBio测序如何改进动植物的基因组。深入了解这项研究。

Pennisi, E., 2017. New technologies boost genome quality. Science. Jul 7;357(6346):10-11.

若有意了解SMRT测序如何支持动植物科学研究,请联系我们

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