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推动基因组学研究,促进全球健康

通过对病原体及其移动元件和群落的全面表征,发现更好的疫苗、疗法和结果。

通过深入的基因组分析加速您的研究

单分子实时(SMRT)测序所带来的综合遗传信息大大增加了我们对微生物基因组学、致病性和耐药性的了解。PacBio系统让科学家能够:

研究聚焦:利用SMRT测序破译病原体的基因组复杂性

科学家能够成功克服众所周知的恶性疟原虫(Plasmodium falciparum)基因组AT偏倚的挑战。从头组装揭开了基因组结构和复杂性的新视角,为更好地了解毒力、耐药性和疾病转播提供了参考。深入了解这项研究:

Vembar, S.S. et al., 2016. Complete telomere-to-telomere de novo assembly of the Plasmodium falciparum genome through long-read (>11 kb), single molecule, real-time sequencing. DNA Research, 23(4), pp.339–351.

研究聚焦:通过单分子测序追踪HIV-1突变

新型环状一致性序列算法的开发让人们得以追踪临床样本中K103N耐药性相关突变的病毒进化。深入了解这项研究:

Laird Smith, M. et al., 2016. An improved circular consensus algorithm with an application to detect HIV-1 Drug Resistance Associated Mutations (DRAMs). In 2016 ASM Microbe. New Orleans, LA.

若有意利用SMRT测序推动基因组学并促进健康,请联系我们

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