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利用微生物的潜能

为了满足全球对医药产品、环境修复和化学品生产的需求,微生物学生物技术必须立足于完整的基因组信息的基础之上。

通过微生物基因组和群落的确信表征推进生物技术研发

PacBio系统单分子实时(SMRT)测序的出现带来了个体生物和微生物群落的更全面视图,可推动科学家开发微生物产品的探索研究。有了PacBio测序,科学家就能够:

研究聚焦:食品生产中微生物之间的遗传差异

科学家利用SMRT测序,以物种水平的分辨率查看手工奶酪生产中所用的细菌微生物。他们的结果证明了哈萨克斯坦境内和境外奶酪生产过程中的微生物多样性。深入了解这项研究:

Li, J. et al., 2017. Bacterial microbiota of Kazakhstan cheese revealed by single molecule real time (SMRT) sequencing and its comparison with Belgian, Kalmykian and Italian artisanal cheeses. BMC Microbiology, 17(1), p.13.

研究聚焦:追踪微生物生产改良的遗传基础

科学家利用长读长测序来构建完整的微生物基因组,以追踪细菌的基因重排事件,其目标是提高丙酸的产量。深入了解这项研究:

Luna-Flores, C.H. et al., 2017. Improved production of propionic acid using genome shuffling. Biotechnology Journal, 12(2), p.1600120.

若有意了解如何运用SMRT测序来提高工业微生物学的效率和推进发现,请联系我们

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