Friday, February 5, 2021

User Group Meeting: Multiple expressed isoforms of TIN2 stimulate human telomerase

In this PacBio User Group Meeting lightning talk, Alexandra Pike of MIT presents a study of TIN2, a telomere-binding protein, which is mutated in some short telomere syndromes. By pairing the Iso-Seq method with CRISPR, her team revealed a previously uncharacterized TIN2 isoform that may have a functional difference for individuals with these syndromes.

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