Friday, February 5, 2021

SMRT Leiden: Improved phased assembly using HiFi data

In this SMRT Leiden 2020 Online Virtual Event presentation, Ivan Sovic of PacBio shares work on a new tool for improved and phased assembly of HiFi data called IPA. IPA delivers highly accurate and contiguous phased assemblies at very high speeds – it can assemble, phase and polish a 34x human genome dataset in just 14 hours on a single 80 core machine, with the final base quality >Q50. IPA constructs true haplotigs through a dedicated phasing process resulting in high phasing accuracy and haplotype separation of the assembly, as well as very high BUSCO gene completeness scores.

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