fbpx
X

Quality Statement

Pacific Biosciences is committed to providing high-quality products that meet customer expectations and comply with regulations. We will achieve these goals by adhering to and maintaining an effective quality-management system designed to ensure product quality, performance, and safety.

X

Image Use Agreement

By downloading, copying, or making any use of the images located on this website (“Site”) you acknowledge that you have read and understand, and agree to, the terms of this Image Usage Agreement, as well as the terms provided on the Legal Notices webpage, which together govern your use of the images as provided below. If you do not agree to such terms, do not download, copy or use the images in any way, unless you have written permission signed by an authorized Pacific Biosciences representative.

Subject to the terms of this Agreement and the terms provided on the Legal Notices webpage (to the extent they do not conflict with the terms of this Agreement), you may use the images on the Site solely for (a) editorial use by press and/or industry analysts, (b) in connection with a normal, peer-reviewed, scientific publication, book or presentation, or the like. You may not alter or modify any image, in whole or in part, for any reason. You may not use any image in a manner that misrepresents the associated Pacific Biosciences product, service or technology or any associated characteristics, data, or properties thereof. You also may not use any image in a manner that denotes some representation or warranty (express, implied or statutory) from Pacific Biosciences of the product, service or technology. The rights granted by this Agreement are personal to you and are not transferable by you to another party.

You, and not Pacific Biosciences, are responsible for your use of the images. You acknowledge and agree that any misuse of the images or breach of this Agreement will cause Pacific Biosciences irreparable harm. Pacific Biosciences is either an owner or licensee of the image, and not an agent for the owner. You agree to give Pacific Biosciences a credit line as follows: "Courtesy of Pacific Biosciences of California, Inc., Menlo Park, CA, USA" and also include any other credits or acknowledgments noted by Pacific Biosciences. You must include any copyright notice originally included with the images on all copies.

IMAGES ARE PROVIDED BY Pacific Biosciences ON AN "AS-IS" BASIS. Pacific Biosciences DISCLAIMS ALL REPRESENTATIONS AND WARRANTIES, EXPRESS, IMPLIED OR STATUTORY, INCLUDING, BUT NOT LIMITED TO, NON-INFRINGEMENT, OWNERSHIP, MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL Pacific Biosciences BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, PUNITIVE, OR CONSEQUENTIAL DAMAGES OF ANY KIND WHATSOEVER WITH RESPECT TO THE IMAGES.

You agree that Pacific Biosciences may terminate your access to and use of the images located on the PacificBiosciences.com website at any time and without prior notice, if it considers you to have violated any of the terms of this Image Use Agreement. You agree to indemnify, defend and hold harmless Pacific Biosciences, its officers, directors, employees, agents, licensors, suppliers and any third party information providers to the Site from and against all losses, expenses, damages and costs, including reasonable attorneys' fees, resulting from any violation by you of the terms of this Image Use Agreement or Pacific Biosciences' termination of your access to or use of the Site. Termination will not affect Pacific Biosciences' rights or your obligations which accrued before the termination.

I have read and understand, and agree to, the Image Usage Agreement.

I disagree and would like to return to the Pacific Biosciences home page.

Pacific Biosciences
Contact:
Wednesday, March 28, 2018

Bio-IT World: Genomic Data Standards Are a ‘Necessity’

Aaron Wenger, Ph.D Genomic data standards will be essential for continuing the growth of genomics and ensuring its smooth transition into the clinic, according to a new Bio-IT World article written by PacBio scientist Aaron Wenger. The piece nicely sums up recent efforts from the Genome in a Bottle Consortium, the Genome Reference Consortium, and the Global Alliance for Genomics and Health to paint a picture of the state of genomic data standard development today. “The more we learn about the human genome, the more needs we identify for data standards,” Wenger reports. “For example, early efforts focused on ensuring…

Read More »

Tuesday, March 20, 2018

New Cattle Genome Overcomes Challenges of Haplotype Assembly

Genetic knowledge is powerful when it comes to breeding. The ability to trace desirable traits to the gene level can help create plants and animals that are adapted to existing and emerging challenges, such as temperature tolerance, productivity, or disease resistance.   By crossing two breeds of cattle, Angus (Bos taurus taurus) and Brahman (Bos taurus indicus), from opposite ends of the species spectrum, breeders can benefit from the Angus’s high productivity in cool environments and the Brahman’s tolerance for harsh, hot climates and the diseases and parasites found there. Genetically and phenotypically, the two subspecies are very different. And,…

Read More »

Monday, March 19, 2018

New High-Quality Swedish Genome Assemblies Identify Novel Population-Specific Reference Sequence

UPDATE: This paper has now been published in Genes.   A new preprint from scientists at Uppsala University’s SciLifeLab reports the de novo genome sequencing and assembly of two Swedish individuals using PacBio SMRT Sequencing. By comparing the Swedish genomes to the human reference (GRCh38), the team found a substantial amount of novel sequence which is not present in the reference – along with over 17,000 structural variants. Further comparison of the Swedish genomes to other population-specific reference genome assemblies – including a Korean and a Chinese genome – identified novel sequences that appear to be population-specific as well as…

Read More »

Thursday, March 15, 2018

Study: SMRT Sequencing Can Improve the Safety of Gene Therapy Protocols

A new publication in the journal of the American Society of Gene & Cell Therapy demonstrates the novel use of SMRT Sequencing for improving the safety and quality of a type of gene therapy delivered through a viral vector. The work established new quality control standards and revealed previously undetected risks for gene therapy delivery. “Adeno-Associated Virus Genome Population Sequencing Achieves Full Vector Genome Resolution and Reveals Human-Vector Chimeras,” published in Molecular Therapy — Methods & Clinical Development, comes from lead author Phillip Tai, senior author Guangping Gao, and collaborators from the University of Massachusetts Medical School and other institutions.…

Read More »

Monday, March 12, 2018

A New Look at an Old Favorite: Cabernet Sauvignon Study Generates a Transcriptome of Ripening Berries

Photo by H. Zell UPDATE: The study has been published in the journal G3: GENES, GENOMES, GENETICS and featured on its cover. ORIGINAL POST (March 12, 2018): A new preprint from scientists at the University of California, Davis, demonstrates the usefulness of SMRT Sequencing and the Iso-Seq method to enable comprehensive transcriptome analysis even in the absence of a reference genome assembly. The team conducted this study on the grape used to make Cabernet Sauvignon. Lead author Andrea Minio, senior author Dario Cantu, and collaborators used SMRT Sequencing to generate full-length transcripts of Vitis vinifera cv. Cabernet Sauvignon, analyzing RNA…

Read More »

Friday, March 9, 2018

Coral Microbiome Project Wins 2017 Microbial SMRT Grant

Rice coral (Montipora capitata) growing over Porites lobata. Credit: Dr. Dwayne Meadows, NOAA/NMFS/OPR Corals are critical to sustaining sea life in many parts of the world, contributing to an elaborate ecosystem that lives in and around their mineralized calcium carbonate skeletons. In addition to hosting photosynthetic endosymbionts in exchange for energy, corals harbor a diverse microbial community. What role does this microbial metagenome play in the health of the coral reef, especially during thermal challenges induced by climate change? Alexander Shumaker of Rutgers University will get a chance to investigate this question, thanks to long-read sequencing provided by PacBio and…

Read More »

Wednesday, March 7, 2018

New Software, Polymerase for Sequel System Boost Throughput and Affordability

Today we’re pleased to announce the release of a new version of Sequel Software (V5.1) and a new polymerase. Combined, these upgrades increase throughput and overall performance for key SMRT Sequencing applications such as de novo assembly, structural variant detection, targeted sequencing, and RNA sequencing using the Iso-Seq method. Orders for the new products can be submitted today. With this release, the Sequel System can achieve up to 10 Gb per SMRT Cell for de novo genome assembly, effectively doubling the throughput when using ultra-long inserts (>40 kb). For targeted and RNA sequencing, customers can achieve up to 20 Gb…

Read More »

Monday, March 5, 2018

Dog Meet Dog World: Exploring Canine Genomes

  UPDATE (October 2020): Sandy’s genome assembly is now available here.   From wild animals to perfect pets, dogs have undergone some interesting changes during their centuries-long domestication. Intent on unraveling some of the developmental secrets of the process, a team of scientists from the University of New South Wales in Sydney, Australia, is doing deep dives into the genomes of a range of canine cousins along the evolutionary chain. A desert dingo named Sandy has already provided some insight into the process after its genome was sequenced as part of the 2017 Plant and Animal SMRT Grant. Study leader…

Read More »

Subscribe for blog updates:

Archives

Search

Categories

Press Release

PacBio Grants Equity Incentive Award to New Employee

Friday, December 3, 2021

Stay
Current

Visit our blog »