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Tuesday, January 5, 2016

Exploring Large Genomes at the Largest Ag Genomics Meeting in the World: PAG 2016

We’re looking forward to the International Plant and Animal Genome conference, taking place January 9-13 in San Diego. PAG features leading plant and animal scientists from around the world, and we’re continually impressed by their new discoveries and creative approaches to understanding large and complex genomes. This year PAG attendees will have a number of opportunities to learn more about how SMRT Sequencing reveals new information about even well-characterized plant and animal genomes. We’ll be exhibiting in booth #421 — and showing off our new Sequel System — so please stop by and tell us about your work. We’ll also…

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Friday, January 23, 2015

Breaking New Frontiers in Grass Genomics to Understand Drought Tolerance with the 2014 SMRT Grant Program Winner: Oropetium thomaeum

Emerging from a myriad of interesting genome nominations, from the American cranberry to South American prawns and African Guava, Oropetium thomaeum submitted by Todd Mockler at the Donald Danforth Plant Science Center was selected as the first winner of the “Most Interesting Genome in the World” SMRT® grant program in 2014.  Also affectionately known as Oro, this grass species can be  revived with water after a long drought exposure. At 250 Mb, the genome is also the smallest amongst grasses due to compaction of complex repeat and gene structures, including previously identified expansions in osmoprotectant biosynthesis pathways. Kicking off the…

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Tuesday, January 20, 2015

Looking Ahead: The 2015 PacBio Technology Roadmap

By Jonas Korlach, Chief Scientific Officer All of us at Pacific Biosciences are very proud of the momentum SMRT® Sequencing achieved in 2014, especially due to the more than 500 customer publications now in the literature describing its many applications. We remain deeply thankful to all the scientists who have applied our technology to gain new insights into genomes, transcriptomes, and epigenomes. By applying SMRT Sequencing to a wide variety of applications, our customers are demonstrating that long, unbiased reads have brought about new quality standards for many fields of genomic research. This exciting level of scientific activity and collaboration…

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Tuesday, January 6, 2015

PAG 2015: SMRT Sequencing and the “Most Interesting Genome” Grant Program

The 23rd annual International Plant and Animal Genome meeting is right around the corner – it’s taking place January 10-14 in sunny San Diego. The meeting has become an important venue for customers showcasing their Single Molecule, Real-Time (SMRT®) Sequencing data on complex plant and animal genome projects. This year, more than 50 researchers from around the world will be presenting their work, many representing large consortium efforts, using SMRT Sequencing to assemble de novo references and/or to analyze complex genomes of a variety of plants and animals. This includes data generated with our Iso-Seq™ application for full-length transcript sequencing. …

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Wednesday, January 29, 2014

At Plant & Animal Genome Workshop, Users Showcase Projects Enabled by SMRT Sequencing

Earlier this month, we hosted a workshop at the International Plant & Animal Genome (PAG) conference in San Diego entitled “A SMRT® Sequencing Approach to Reference Genomes, Annotation, and Haplotyping.” PacBio users presented data on various projects that have benefited from long-read sequence data, including several that had previously been attempted with short-read technologies without success. We were delighted to see reports on newer features of SMRT Sequencing, including full-length isoforms, automated haplotyping, and more. Here’s a recap, as well as links to video recordings of the presentations: Chongyuan Luo, a scientist from Joe Ecker’s lab at the Salk Institute…

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Wednesday, January 8, 2014

SMRT Sequencing for Plant and Animal Genomes: Learn More at PAG 2014

Many recent studies have demonstrated the use of Single Molecule, Real-Time (SMRT®) Sequencing for larger genomes, from complete reference genomes to de novo discovery of transcript isoforms. These advances include understanding genome complexity and variation and enabling improved leverage of haplotype information for biotechnology. Some of these efforts will be presented at the workshop we’re hosting at this year’s International Plant & Animal Genome (PAG) conference in San Diego. Sign up now to reserve your seat or receive the recording after the event.  Workshop details: A SMRT® Sequencing Approach to Reference Genomes, Annotation, and Haplotyping Tuesday, January 15 1:30 –…

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Thursday, February 7, 2013

PAG Highlights and Workshop Recording: Generating High-Quality Bacterial, Plant and Animal Genomes

It was great to visit sunny San Diego for the International Plant and Animal Genome meeting last month. We were impressed with the quality of talks and posters, and we appreciated all the scientists who stopped by our booth or attended our workshop. One highlight for us was listening to Kim Worley from Baylor’s Human Genome Sequencing Center as she described a sooty mangabey primate genome project. Sooty mangabey is a model organism for HIV research, since this particular primate can be infected with the immunodeficiency virus and never develop any symptoms. Because this resistance likely comes from a complex…

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Friday, January 11, 2013

PAG 2013 – What Would You Do with a Complete Genome?

We’re pleased to be hosting a workshop at the 21st annual International Plant & Animal Genome conference in San Diego next week — and whether you’re attending or not, we invite you to participate. The workshop will focus on generating high-quality bacterial, plant, and animal genomes using SMRT® Sequencing technology. If you’ll be at PAG, we encourage you to reserve a seat to attend the event. If not, sign up to receive a recording of the workshop. Our event will take place on Tuesday, January 15th from 1:30 to 3:30 p.m. in the San Diego Room. We’ll have presentations from…

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