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Thursday, August 24, 2017

Software Tools Optimized for Long Reads Improve Detection of Complex Structural Variants

Sniffles and NGMLR, structural variant detection and alignment algorithms developed in the Schatz lab for long-read sequence data, are already familiar to many in the PacBio community. Now, a preprint is available so users can see how these open-source tools perform in a variety of conditions. “Accurate detection of complex structural variations using single molecule sequencing” comes from lead author Fritz Sedlazeck at Baylor College of Medicine, senior author Michael Schatz at Johns Hopkins University, and collaborators. The team notes that long-read sequencing has introduced a much more comprehensive means of discovering structural variants, many of which are missed by…

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Tuesday, January 5, 2016

Exploring Large Genomes at the Largest Ag Genomics Meeting in the World: PAG 2016

We’re looking forward to the International Plant and Animal Genome conference, taking place January 9-13 in San Diego. PAG features leading plant and animal scientists from around the world, and we’re continually impressed by their new discoveries and creative approaches to understanding large and complex genomes. This year PAG attendees will have a number of opportunities to learn more about how SMRT Sequencing reveals new information about even well-characterized plant and animal genomes. We’ll be exhibiting in booth #421 — and showing off our new Sequel System — so please stop by and tell us about your work. We’ll also…

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