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お問い合わせ

生物種内、生物種間の遺伝多型の特徴づけ

全ゲノムシークエンスは生物における完全なDNAの構成を明らかにし、遺伝的および後生的な多型により詳細な解像度をもたらします。現在の技術では、ゲノムシークエンスをするにはまずゲノムを小さく断片化し、その後でde novoアセンブリ、あるいは既存のリファレンス配列にマッピングすることで繋げ直すプロセスが使われています。パズルを解き明かすのと同様、大きなゲノム断片であれば繋げ直す作業も容易に行えます。

ゲノムシークエンスに「全」をもたらす

1分子リアルタイム (SMRT) シークエンスは、最も高精度なコンセンサス配列と均一なゲノムカバレッジをもたらすロングリードにより、断片化されたドラフトゲノムではなく、最も包括的なde novoアセンブリを可能にします。PacBioシステムがもたらす真の全ゲノムシークエンスは、SNP/SNVから構造多型、移動因子、ハプロタイプ、エピジェネティクス、そして複雑性の低い領域における多型まで、すべての種類のゲノム多型を包括的かつ高精度に検出することができます。

 

PacBioは全ゲノムシークエンスに包括的なソリューションと高度なアプリケーションを提供します

SMRTシークエンスProject Calculator

全ゲノムシークエンス用のプロジェクトCalculatorを使い、Sequel システム利用時の必要時間、材料を予測しましょう。

PacBioの全ゲノムシークエンスについての詳細は ぜひお問い合わせください。

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