(Subscription required) A team led by researchers at the US DOE’s JGI has successfully created high-resolution phylogenetic profiles for microbial communities using the PacBio RS II platform to generate full-length 16S rRNA sequences, which the researchers have dubbed PhyloTags.
Sequencing firms as well as manufacturers of ancillary equipment and reagents continue to innovate, releasing tools that will both extend the ongoing democratization of technology access and streamline the sample-preparation workflows that drive that equipment on the front end.
A biotech company in Menlo Park is getting widespread attention through a cutting-edge tool it has developed for genetic research.
Biotechniques reviews the best uses for different DNA sequencing technologies, and how sometimes a combination works best.
(Subscription required) CEO Mike Hunkapiller provided attendees of the JP Morgan Healthcare conference an update on the company’s progress, including orders for 49 Sequel Systems in its first quarter of sales.
(Subscription required) – Researchers at Baylor College of Medicine are exploring whether PacBio long sequence reads can detect genetic disease mutations that would otherwise go unnoticed.
Aaron Krol provides an in-depth look at the use of SMRT Sequencing at the Icahn School of Medicine at Mount Sinai.
PacBio’s own Luke Hickey provides an overview of efforts to create reference-quality human genomes in this contributed article.
The genome of Tardigrades, or water bears, was decoded using PacBio sequencing revealing how they are a ‘sponge’ for foreign genes.
Researchers reported in Nature the virtually complete draft genome of Oropetium thomaeum, a grass species that can regrow after exposed to extreme drought when water becomes available.
(Subscription required) Researchers who spoke during a panel discussion at the Festival of Genomics conference in San Mateo, California this week, said that although challenges continue to persist, they are more or less solvable as long as you know what the problem is and the correct technology to use to solve it.
Pacific Biosciences has launched a new nucleic acid sequencing platform called Sequel.
(Subscription required) Pacific Biosciences said that in the first two weeks since it launched its Sequel System, it has received as many requests for quotes as it did collectively in the prior nine months for its RS II system, and several of those requests have turned into sales.
Sequencing is becoming less ambiguous and more clinically relevant with advances in technology.
(Subscription required) At the American Society of Human Genetics annual meeting in Baltimore last week, PacBio Chief Scientific Officer Jonas Korlach and Executive Vice President and Chief Financial Officer Susan Barnes offered additional insights into the design and roll-out of the new platform.