(Subscription required) Researchers who spoke during a panel discussion at the Festival of Genomics conference in San Mateo, California this week, said that although challenges continue to persist, they are more or less solvable as long as you know what the problem is and the correct technology to use to solve it.
Pacific Biosciences has launched a new nucleic acid sequencing platform called Sequel.
(Subscription required) Pacific Biosciences said that in the first two weeks since it launched its Sequel System, it has received as many requests for quotes as it did collectively in the prior nine months for its RS II system, and several of those requests have turned into sales.
Sequencing is becoming less ambiguous and more clinically relevant with advances in technology.
(Subscription required) At the American Society of Human Genetics annual meeting in Baltimore last week, PacBio Chief Scientific Officer Jonas Korlach and Executive Vice President and Chief Financial Officer Susan Barnes offered additional insights into the design and roll-out of the new platform.
Pacific Biosciences has launched a new single-molecule sequencing system that offers higher throughput and costs about half the price of its RS II system.
The Sequel System provides higher throughput, more scalability, a reduced footprint and lower sequencing project costs compared to the PacBio RS II System, while maintaining the existing benefits of the company’s SMRT Technology.
(Subscription required) PacBio laid out plans to change the output of its instrument and analysis software packages from the Hierarchical Data Format (HDF5) to the more commonly used Binary Alignment/Map (BAM) file format for both raw and aligned sequencing reads.
While not about PacBio specifically, we thought this editorial would be of interest to the SMRT Sequencing community.
(Subscription required) During a conference call discussing its second quarter performance, CEO Mike Hunkapiller gave an overview of the single-molecule sequencing company’s position in the market and expansion plans.
PacBio CSO Jonas Korlach discusses the implications for SMRT Sequencing in clinical research.
Researchers have reported an important advance for using SMRT sequencing for epigenetic studies with a new approach capable of probing epigenetic heterogeneity in a population of seemingly identical bacteria.
GenomeWeb: The UK’s Anthony Nolan Research Institute plans to start using Pacific Biosciences’ sequencing technology routinely for HLA typing by the end of this year after scientists from the institute and PacBio published a feasibility study this spring.
A team of scientists has published one of the most detailed explorations to date of complex structural variation in a human genome. The results highlight just how much genomic variation is missed when working exclusively with short-read sequencing technologies.
A collaboration of scientists led by researchers from Icahn School of Medicine at Mt. Sinai has created a comprehensive analysis of a diploid human genome using two complementary single DNA molecule methods for sequencing and genome mapping, and without the need for any DNA amplification techniques.